Research can not be done in isolation. Collaborations are essential to the advancement of science. Combining expertise and providing tools and technologies helps us achieve greater possibilities. We help and are helped by many different labs. Some of our past and present collaborators are listed below.
We are working with Ravi Sachidanandam and his group of computational biologists to better understand how gene expression, and microRNAs in particular, are regulated.
Our group is working closely with Miriam Merad and her lab to uncover the regulatory networks that control dendritic cell and macrophage biology. This includes our work together as part of the Immgen consortium (below). We are also working to identify factors that control the immune microenvironment in tumors.
We collaborate closely with Josh Brody and his team to determine the genes used by lymphomas to resist antigen-dependent T cell elimination. We have developed a novel screening platform that is enabling us to look at the darwinian evolution of tumors under the selective pressure of antigen-specific Jedi T cells.
We are collaborating with Emily Bernstein and her lab to try and understand how chromatin regulators control cancer cell behavior and resistance to targeted therapies.
We are members of the Immgen Consortium, an NIH funded project led by Dr. Christoph Benoist, whose goal is to determine the complex molecular networks that control and connect all cells in the immune system. The Immgen Consortium has already profiled more than 200 different cell types of the immune system, and made the data available to the public, in a highly accessible format.
In collaboration with Matthew Evans, we studied the regulatory interactions between hepatitis C virus and host cell microRNAs.